According to the manufacturer controlledclinical trial, Valsartan significantly reduced hospitalizations for heart failure. Stopping Entresto will not cause withdrawal symptoms, but there is a risk of rebound high blood pressure if other blood pressure drugs are not being taken. Fortunately, most medications won't cause a problem if you stop them suddenly. Learn more about how long it takes for Entresto to work, what its used for, how to take it, its side effects, and some commonly asked questions about it. Journal of the American College of Cardiology. Phase IV trials are used to detect . Entresto can cause harm or death to your unborn baby. I am on Entresto. Common side effects of Entresto include: low blood pressure. ENTRESTO is a film-coated tablet that comes in the following doses: 24/26 mg, 49/51 mg, and 97/103 mg. Wait 36 hours when switching from Entresto to an ACE inhibitor, 4. Entresto may make you feel light-headed, faint, or cause you to feel extreme tiredness. NYHA class II-IV is identified as mild to severe heart failure. Increased amounts of sodium and fluid in those with heart failure often leads to symptoms of swelling, weight gain, and shortness of breath. This means you will need to stop taking all ACE inhibitors or ARBs for 36 hours prior to starting Entresto. Drugs You Should Never Stop Suddenly. It is important to take lisinopril every day even if your blood pressure is not elevated. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Enalapril is used for the treatment of symptomatic congestive heart failure. The risk of relapse is a great concern, says Henderson. Take the next dose at your regular time, If you take too much Entresto, call your healthcare provider right away or go to the nearest emergency room, Discontinue Entresto as soon as possible when pregnancy is detected, It is not known if Entresto passes into your breast milk. Think about that these were desperate heart failure patients who decided theyd rather take their chances without the drug. These two active ingredients work in different ways. It is proving to be an uphill struggle between the strong desire on the part of the cardiologist and myself for this highly thought of drug for treating heart failure to work, and the actual fact of the every increasing deeply unpleasant side effects. Talk with a healthcare provider to discuss medical conditions, 2. If any Dispute cannot be resolved informally, you agree that any and all Disputes, including the validity of this arbitration clause and class action waiver, shall be submitted to final and binding arbitration before a single arbitrator of the American Arbitration Association (AAA) in a location convenient to you or telephonically. The more common side effects of bisoprolol oral tablet include: slower heart rate. Entresto can also cause a side effect called angioedema, an allergic reaction that can trigger a sudden swelling in your face and neck that can choke you. Spironolactone is used for the treatment of heart failure (NYHA Class III-IV) and reduced ejection fraction to increase survival, manage edema (swelling caused by trapped fluid in tissues), and reduce the need for hospitalization for heart failure. showed patients had decreased systemic vascular resistance, blood pressure, pulmonary capillary wedge pressure and heart size, and increased cardiac output and exercise tolerance. Entresto may have done a . If you have rapid weight changes it may be that your heart failure is getting worse. Been on Entresto 49/51 for about 2 months now noticed some benefit but need to have another eco in about 2 months time to check EF rates. Anticoagulants like Coumadin, a type of blood thinner, should always be taken as directed and never stopped without your doctors knowledge. Tapering is important; the faster you quit antidepressants cold turkey, the more you increase your risk of relapsing back into a depression again. The phase IV clinical study analyzes what interactions people who take Entresto and Aspirin have. Bisoprolol works as well as other beta blockers for reducing blood pressure, but it's less likely to cause side effects.. That's because bisoprolol works mainly on the heart. You may also need to avoid taking Entresto with aliskiren if you have kidney disease. Medications take the lion's share of responsibility for improvement in EF over time. What happens if you suddenly stop taking Entresto? Can you stop atorvastatin suddenly? Theres an incentive to find the right treatment, stay on that treatment, and prevent the illness from coming back, says Henderson. It is not an ACE inhibitor but is an angiotensin receptor blocker and neprilysin inhibitor. But what many people don't realize is that stopping certain drugs abruptly can make you sick or, in rare instances, even kill you. entresto 24/26 mg, cardivedol6.25mg no symptoms at present..I take both of these in the am and evening, I took those and sthen when I went to bed I accidentally took these meds again. In 2022, the manufacturer of Entresto (Novartis) states that around 80% of individuals with Medicare Part D prescri Entresto is a popular brand-name drug used to treat congestive heart failure. According to the. For this reason, it is not a good idea to suddenly halt usage of atorvastatin, even among patients worried about side effects of the medication. Things to consider. Honestly, I had less pain during my heart attack. Valsartan is one of two medications in Entresto and is available individually as a tablet. Maybe: Losartan can cause cough. After numerous requests, the doctor switched Entresto to Lisinopril. Prozac Withdrawal - What Are the Symptoms & How Long Do They Last? Entresto warnings. According to the manufacturer, enalapril showed effectiveness when used with other heart failure medications, digitalis, and diuretics. tiredness. Informational purposes only. Approved by the FDA in 2015, Entresto is a combination tablet of two different medications: an angiotensin II receptor blocker (valsartan) and a neprilysin inhibitor (sacubitril). What is the half life of Entresto? Your exact dose will be based on your age, weight, and the condition you are being treated for. Entresto (sacubitril/valsartan) is a prescription medication used to reduce the risk of cardiovascular death and hospitalization in adult patients with chronic heart failure. Bottom Line. When you provide your telephone number on this website or send a text message to us with or from a short-code, you agree to receive alerts and communications, and marketing messages including those sent via automated telephone dialing system, text messages, SMS, MMS, and picture messages from Institute of Health Sciences, L.L.C at the phone number you provide on this website or the phone number from which you text the short code, including on landlines and wireless numbers, even if the phone number is on a corporate, state or national Do Not Call list. It is an angiotensin receptor neprilysin inhibitor (ARNI), which contains two active ingredients: sacubitril (a neprilysin inhibitor), and valsartan (an angiotensin receptor blocker or ARB). Tips. Vitamin B1 helps the body make food into energy. I have taken these three times today. Pursuant to any applicable statutes, regulations, rules, ordinances or other laws, including without limitation the United States Electronic Signatures in Global and National Commerce Act, P.L. According to the Journal of the American College of Cardiology, natural alternatives are not included in the standard treatment for heart failure. This class of drugs works by . Additionally, these two medications can decrease the amount of sodium and fluid in the body. But Entresto blocks neprilysin from doing its job. Your carrier may charge you for text messages and telephone calls that you receive, or may prohibit or restrict certain mobile features, and certain mobile features may be incompatible with your carrier or mobile device. Any progress they've seen on medication is likely to fade once they stop taking their heart drugs, new clinical trial results show.. About 40 percent of a small group of patients wound up back on . changes in sex drive or performance. nausea and vomiting of the entresto. Over 50% of patients reported a negative experience while using Entresto. These two medications work together as an angiotensin receptor-neprilysin inhibitor (ARNI) to widen blood vessels leading to increased blood flow and reduced blood pressure. Please read these terms carefully. With long term use and frequent use of these drugs, a physiological dependence can develop, says David Henderson, MD, professor chair of psychiatry at Boston University School of Medicine. OVERVIEWDOSAGESIDE EFFECTSINTERACTIONSHALF-LIFE, Class: Aldosterone antagonist, potassium-sparing diuretic. If a Dispute arises under this Agreement, you agree to first contact us at 1-888-213-0764 [email protected]. Message & data rates may apply. For example, BiDil must not be used in combination with medications like Viagra (sildenafil) or Cialis (tadalafil). Story highlights. Confusion or restlessness. By providing your telephone number to us, texting us a short code listed on the website, or otherwise indicate your agreement to these Terms and Conditions, you are agreeing to the mandatory arbitration provision and class action waiver below. This fluid retention can cause certain problems to worsen such as kidney, heart, or liver diseases or conditions. Stopping treatment may cause your condition to get worse. Entresto contains the active ingredients sacubitril and valsartan. 5. Now that you know the side effects from stopping certain medications cold turkey, check out the trulybizarre side effects caused by 10 common medications, including thyroid meds. Entresto is a combination medication containing sacubitril and valsartan that may be given to treat heart failure in adults and children over the age of one. If you suddenly stop taking Entresto, watch for signs of the condition you're taking the drug to treat. , Black patients were studied because they may have less nitric oxide in the body than other patients, suggesting better results with BiDil. In the. cough. Vitamin B1 has also shown to increase urination and excretion of sodium in urine in people receiving diuretics, which is a great benefit in heart failure patients. In fact, the FDA approved Entresto and gave Novartis until 2019 to wrap up a study on whether it may cause Alzheimers or dementia. In the. Entresto should not be taken by pregnant women, particularly in the second and third trimesters. We are a community dedicated to support; sharing of experiences, resources, and tips; and fostering safe relationships, with emphasis on heart failure. , Entresto was found superior to enalapril in reducing the risk of the combined endpoint of cardiovascular death or hospitalization for heart failure. In the A-HeFT trial, Black patients were studied because they may have less nitric oxide in the body than other patients, suggesting better results with BiDil. Entresto has been shown to reduce the risk of cardiovascular death or hospitalization for heart failure by 20% after more than 2 years. Speak to your doctor if you experience rapid weight gain while taking Entresto. Always consult with your doctor before changing anything relatedtoyourhealthcare. Only been on it for three weeks. You agree that we may communicate electronically with you and that such communications, as well as notices, disclosures, agreements, and other communications that we provide to you electronically, are equivalent to communications in writing and shall have the same force and effect as if they were in writing and signed by the party sending the communication. At my last check (Feb 2016), and after wearing a 24 hour BP monitor, my cardiologist suggested I start Carvedilol 6.25 1x per day (quite a low dose) for the spikes and to keep the heart from getting too excited. Stop Entresto safely with instructions from a healthcare professional, Hypotension (low blood pressure), dizziness, hyperkalemia (elevated levels of potassium), cough, renal (kidney) failure, 97/103 mg tablet taken by mouth twice daily, Heart failure, hypertension, asymptomatic left ventricular dysfunction, 2.5 to 20 mg tablet taken by mouth twice daily, Heart failure, hypertension, post-myocardial infarction, Hypotension, dizziness, hyperkalemia, diarrhea, arthralgia (non-inflammatory joint pain), back pain, fatigue, Heart failure, hypertension, left ventricular dysfunction following myocardial infarction, Hypotension, dizziness, diarrhea, fatigue, increased blood sugar, weakness, lack of energy, slowed heart rate, weight gain, 6.25 to 25 mg tablet taken by mouth twice daily, Heart failure in specifically Black people, 20/37.5 mg tablet taken by mouth three times daily, Heart failure, hypertension, edema associated with hepatic cirrhosis or nephrotic syndrome, primary hyperaldosteronism, Hyperkalemia, gynecomastia (enlarged breasts in men), electrolyte abnormalities, 12.5 to 50 mg tablet taken by mouth one to two times daily, Heart failure (NYHA class II-IV) with reduced ejection fraction (HFrEF), Type 2 diabetes, chronic kidney disease, Female genital yeast infections, nasopharyngitis (inflammation of the nose and pharynx), urinary tract infections. The dilemma of whether to give the . Compare Entresto alternatives | Enalapril | Valsartan | Carvedilol |BiDil | Spironolactone | Natural alternatives | How to switch meds. , also called CoQ10, is an antioxidant naturally made in the body and is available as a supplement. ARBITRATION IS MANDATORY AND THE EXCLUSIVE REMEDY FOR ANY AND ALL DISPUTES RELATED TO THIS WEBSITE, THIS AGREEMENT, AND ANY TELEPHONE CALLS, EMAILS, OR TEXT MESSAGES THAT YOU RECEIVE FROM OR ON BEHALF OF US, UNLESS SPECIFIED BELOW OR UNLESS YOU OPT-OUT. Some people may consider alternative medications due to cost. The information on this website should not be relied upon and is not a substitute for professional medical advice. Entresto prices will vary depending on the amount you buy and where you buy it from. kidney problems - little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath. How do we know what will happen in the real world? he asked. This washout period helps to minimize the chance of angioedema (swelling under the skin usually in the lips, tongue, face, or throat), which can be life-threatening. It is the primary variant seen today in the united states. diarrhea. A doctor can slowly wean you off of the steroids and ease your body back into making cortisol on its own again without the horrible withdrawal effects. Consultant, Medicine/Cardi. BiDil can be used in non-Black people as well, especially if they are intolerant to other heart failure medications. 4. Entrestos side effects were so bad that 18 percent of trial participants dropped out. Valsartan is 50% eliminated from your body after about 10 hours of taking the Entresto tablet. By texting HSI to 844-539-1128, you are providing your electronic signature expressly consenting to be called and texted (including by prerecorded messages, using an autodialer, and/or automated means) with alerts, stories, reports, and marketing communications from Institute of Health Sciences, LLC. Take the next dose at your regular time. Phase IV trials are used to detect adverse . As important as lifestyle modification is, no medications is not realistic for the vast majority. HOWEVER, YOU UNDERSTAND AND AGREE TO HAVE ANY CLAIMS DECIDED INDIVIDUALLY AND ONLY THROUGH ARBITRATION. While an effective treatment for some people, Entresto may not be the best option for everyone with chronic heart failure. Also called L-carnitine, this nutrient is naturally made in the body and is involved in fatty acid metabolism for the body to make energy. Talk about a case of see no evil, hear no evil, speak no evil. All Rights Reserved. It was concluded that CoQ10 supplementation is safe and well tolerated and is associated with a reduction in symptoms and major adverse cardiovascular events. The igg response generally follows that of igm and involves a larger number of antigens. Some people may consider alternative medications due to cost. Any dispute relating in any way to telephone calls, emails, or text messages that you receive from or on behalf of Institute of Health Sciences, L.L.C this website, or this Agreement (collectively Disputes) shall be submitted to confidential arbitration and shall be governed exclusively by the laws of the State of Maryland, excluding its conflict of law provisions. If you take too much ENTRESTO, call your doctor right away. Spironolactone works by blocking the activity of aldosterone, a steroid hormone associated with water retention. The study determined that BiDil treated participants had a statistically significant 43% reduction in all-cause mortality compared to placebo. Entresto works by blocking the changes caused by the enzyme neprilysin, and angiotensin-II. Coenzyme Q10, also called CoQ10, is an antioxidant naturally made in the body and is available as a supplement. In addition, the second prince rebelled outside, which would have formed what to take for sexual enhancement a trend of internal and external echoes. Call 1-888-213-0764 to learn more. Llchc accepts medicaid and medicare, as well as most private insurance plans. However, alternative medications that have shown improved survival in heart failure include some of the ACE inhibitors, ARBs, beta-blockers, aldosterone antagonists, isosorbide dinitrate/hydralazine, ivabradine, and SGLT2 inhibitors. People who should avoid or switch their Entresto medication to a different heart failure medication include: Entresto is currently only available as a brand-name medication and is often an expensive treatment option even with insurance or Medicare. dizziness. Agitation, confusion, and disorientation are some of the most commonly reported withdrawal symptoms. This article is not medical advice. , treatment with CoQ10 in addition to standard therapy for people with moderate to severe heart failure was studied. Some major drug interactions with Entresto include: There are other medications to treat heart failure that your healthcare professional can prescribe if Entresto is not the right medication for you. Flushing of the face. Also called thiamine, vitamin B1 is a water-soluble vitamin found in foods and is available as a supplement. NYHA class II-IV is identified as mild to severe heart failure. For anyone who may be interested, I have it from a reliable source that Entresto will be added to the PBS (Pharmaceutical Benefits Scheme), in Australia, with effect from 1 June 2017. So far, my blood pressure has been in the mid to upper 90s or low 100s. Its a new heart failure med called Entresto that was just approved by the FDA and some docs say theyre already getting phone calls from patients who are eager to start the drug. I feel more fresh and better. it was proven superior at helping people stay alive and out of the hospital. Without limiting the foregoing, YOU EXPRESSLY AGREE TO SUBMIT TO ARBITRATION ALL DISPUTES RELATING TO ANY TEXT MESSAGES OR TELEPHONE CALLS YOU RECEIVE FROM OR ON BEHALF OF US OR ANY ENTITY WITH WHOM WE MAY SHARE YOUR TELEPHONE NUMBER. If so, don't just discontinue -- you need other medications to control your BP/fluid balance like the Entresto is supposed to. These risks include staying in a hospital due to heart failure and death related to heart failure. Carvedilol is a beta blocker and is usually dosed as a 6.25 to 25 mg tablet taken by mouth twice daily. Your consent is not required to purchase goods or services. Or how its side effects were so debilitating that patients quit Entresto in droves during clinical trials. , this nutrient is naturally made in the body and is involved in fatty acid metabolism for the body to make energy. Mexiletine should be taken with food or an antacid to prevent stomach upset. Vitamin B1 helps the body make food into energy. Withdrawal symptoms from antidepressants arent nearly as dangerous as anti-anxiety meds, but theyre still very uncomfortable. What can happen: If you suddenly stop taking an SSRI or SNRI, you may go through intense physical withdrawal. Lets go on vacation. If you stop taking the steroid suddenly, your bodys adrenal glands will need about a week or two to wake up and start making cortisol again. Entresto can be safely taken alongside many medications. Serious side effects have been reported with Entresto. Magnesium is an important mineral that people get from their diets, however, some people may benefit from additional magnesium supplementation. Since some of these spironolactone withdrawal symptoms can be severe, its important to learn more about them. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. Every doctor Ive known who has patients that have run out or decided they didnt want to take [their anticoagulant] anymore had a stroke because they stopped [taking it], says Grossman. Once again, your doctor can taper the dosage until youre off the medication completely and help you avoid unpleasant withdrawal symptoms. But sometimes we need an extra punch of steroids in our bodies to fight off an acute illness or inflammation. In order to prevent these withdrawal symptoms and seizure risk, your doctor will slowly taper your dosage until your body is safely off the drug entirely. Before joining Readers Digest, she was a Jason Sheftell Fellow at the New York Daily News and interned at Seventeen and FOX News. The following are included in the American College of Cardiology clinical guidelines for the management of heart failure: Enalapril is used for the treatment of symptomatic congestive heart failure. (if your blood pressure is very low then do not take . Stopping Entresto will not cause withdrawal symptoms, but there is a risk of rebound high blood pressure if other blood pressure drugs are not being taken. Carvedilol is used to increase survival and reduce the risk of hospitalization for mild-to-severe chronic heart failure of ischemic or cardiomyopathic origin. This means you will need to stop taking all ACE inhibitors or ARBs for 36 hours prior to starting Entresto. According to the manufacturer, enalapril showed effectiveness when used with other heart failure medications, digitalis, and diuretics. The unborn baby is at risk for harm, renal failure, and death. It comes in these doses because it contains 2 medicines, which enable it to work in 2 ways. Valsartan is an angiotensin receptor blocker. Except as may be required by law as determined by the arbitrator, no party or arbitrator may disclose the existence, content or results of any arbitration hereunder without the prior written consent of both parties. https://www.ncbi.nlm.nih.gov/books/NBK507904/, https://reference.medscape.com/drug/entresto-sacubitril-valsartan-1000010, https://www.novartis.com/us-en/sites/novartis_us/files/entresto.pdf, To reduce the risk of cardiovascular death and hospitalization for heart failure with reduced ejection fraction (HFrEF) in adult patients with chronic heart failure. If you take Isosorbide Dinitrate without a break and then suddenly stop taking it, you may get WITHDRAWAL symptoms. If you miss a dose, take it as soon as you remember. Read more to learn about hypertension causes and treatments. Some alternatives should be used with caution or avoided with certain medical conditions. This is when prescription steroids, like the commonly used prednisone, are valuable. Before formally submitting a Dispute to arbitration, you and we may choose to informally resolve the Dispute. What happens if you suddenly stop taking Entresto? Patients with angioedema often need a breathing tube or a surgical incision in their throats to allow them to breathe. NYHA class III-IV is identified as moderate to severe heart failure and reduced ejection fraction indicates that the left side of the heart doesnt pump blood out to the body as well as normal. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Entresto. A medical professional has reviewed this article. I agreed that maybe it was a good idea and started over two months ago. There is evidence that magnesium likely improves outcomes in people with congestive heart failure by preventing ventricular arrhythmias (a type of abnormal heart rhythm). BiDil is a combination tablet of a nitrate vasodilator (isosorbide dinitrate) and an arteriolar vasodilator (hydralazine) and is usually dosed as a 20/37.5 mg tablet taken by mouth three times daily. is a water-soluble vitamin found in foods and is available as a supplement. Im talking about dangerously low blood pressure, impaired kidney function, and sky-high blood potassium levels that could even stop your heart! Due to the nature of the condition, many people with congestive heart failure are, . You see, your body produces a key enzyme called neprilysin that breaks down the toxic amyloid beta protein that researchers believe causes Alzheimers. 3,183. Remember, you should only take the exact dose as prescribed by your doctor. Entresto may cause side effects, some more serious than others. Tiredness or lethargy. Table of Contents. I am thinking Heart Failure is a little improved Breathing slightly better, only downside is . It improves symptoms, increases survival, and decreases the frequency of hospitalization. Valsartan, generic for Diovan, is used to reduce the risk of hospitalization for heart failure in adult patients with heart failure (NYHA class II-IV). Prada47 4 years ago. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Contact your carrier with questions regarding these issues. FDA approves new drug to treat heart failure FDA News Release, July 7, 2015, fda.gov, Investigators link Novartis would-be cardio blockbuster to Alzheimers risk John Carroll, February 9, 2015, FierceBiotech, fiercebiotech.com, After sinking in, PARADIGM-HF critiqued at HFSA sessions Steve Stiles, September 25, 2014, Medscape, Medscape.com, Copyright 1997 - 2023 by NewMarket Health Publishing, LLC1117 St. Paul Street, Baltimore, MD 21202, USA. Due to the nature of the condition, many people with congestive heart failure are deficient in magnesium. Stop Entresto safely with instructions from a healthcare professional. Of course, by then millions of people will be taking the pill. Effexor withdrawal, a common form of antidepressant discontinuation syndrome, occurs if you abruptly stop taking it. Antianginal Nursing Implications o Encourage pt to limit caffeine o Report any pulse less than 60bpm, weight gain of 5lb in 1 week, edema or blurred vision o Alcohol consumption and time in hot environments will cause vasodilation, hypotension and possible fainting Chapter 24 Heart Failure o Left-sided - Pulmonary edema, coughing, shortness of breath . Here's a look at some drugs that can cause serious issues if you stop them cold-turkey. People taking Entresto should immediately inform their healthcare provider of a pregnancy or plans to become pregnant. Do not refrigerate Entresto oral suspension, Store Entresto tablets at room temperature between 68F to 77F (20C to 25C) away from moisture, Worsening kidney disease or function, especially in those with, Angioedema (swelling of your face, lips, tongue, and throat) and hypotension (low blood pressure), Allergic reactions discontinue Entresto immediately and seek medical advice if you have symptoms such as hives, trouble breathing, or swelling of your face, lips, tongue, or throat, Increase in potassium levels. Only stop taking Entresto if the prescribing doctor has been consulted and decided stopping the medication is safe. Msg&data rates may apply. YOU UNDERSTAND THAT YOU WOULD HAVE HAD A RIGHT TO LITIGATE IN A COURT, TO HAVE A JUDGE OR JURY DECIDE YOUR CASE AND TO BE PARTY TO A CLASS OR REPRESENTATIVE ACTION. Two to three million Americans take blood thinners, medicines that prevent blood clots from forming, according to WebMD. 1. Patients with hyperkalemia (high potassium), Patients with Addisons disease (hypocortisolism or adrenal insufficiency), Patients who are using eplerenone (Inspra). Entresto is a combination of two medications. 26,038 satisfied customers. Free coupons for Entresto are available from, Entresto helps improve survival in people with heart failure. Since Entresto is the only medication in the angiotensin receptor-neprilysin inhibitor (ARNI) class, there are no available alternatives within the same drug class. A washout period of 36 hours is required prior to starting Entresto. You also might need a different dose if you have kidney or liver problems. Your doctor may also suggest that you stop taking Entresto. Created for people with ongoing healthcare needs but benefits everyone. The general rule of thumb for antidepressants: If a patients symptoms improve after taking the medication for six months to a year, then the doctor can consider tapering them off. NYHA class III-IV is identified as moderate to severe heart failure and reduced ejection fraction indicates that the left side of the heart doesnt pump blood out to the body as well as normal. Now, 30 tablets is $9, and 90 tablets is $24. Only stop taking Entresto if the prescribing doctor has been consulted and decided stopping the medication is safe. Blood pressure levels can also increase after stopping the use of this medication. If you were to stop taking it suddenly the beta-blocker could have a rebound effect like a racing heart. In fact, a rebound episode could result in ischemia of the heart and a dramatic rise in blood pressure and heart rate.